BDBM50596945 CHEMBL5207529

SMILES COc1cc(OC)c(cc1OC)C1NCCc2c1[nH]c1ccc(Cl)cc21

InChI Key InChIKey=RJHMAXLLXKUOBW-UHFFFAOYSA-N

Data  13 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50596945   

Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.468nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.575nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.580nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  22nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  25nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  29nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  39nMAssay Description:Binding affinity to 5HT1D receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  52nMAssay Description:Binding affinity to 5HT1B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  70nMAssay Description:Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  113nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  666nMAssay Description:Binding affinity to 5HT1E receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  1.48E+3nMAssay Description:Binding affinity to beta1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.79E+3nMAssay Description:Binding affinity to 5HT3 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed