BDBM50596946 CHEMBL5182943

SMILES Cl.COc1cc(OC)c(cc1OC)C1NCCc2c1[nH]c1ccc(F)cc21

InChI Key InChIKey=LWHOEIHANZIFDG-UHFFFAOYSA-N

Data  12 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50596946   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  56nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  249nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  530nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  660nMAssay Description:Binding affinity to 5HT1D receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  671nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  760nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  961nMAssay Description:Binding affinity to beta1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  964nMAssay Description:Binding affinity to alpha2c (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  1.37E+3nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  2.33E+3nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  2.45E+3nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataKi:  2.84E+3nMAssay Description:Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed