BDBM50596988 CHEMBL5189965

SMILES Nc1cc(c2SCCCCCC[C@@](O)(c3nnc(o3)-c1n2)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=FMTOZCUICKNRFG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50596988   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50596988(CHEMBL5189965)
Affinity DataEC50: <500nMAssay Description:Modulation of CFTR F508 deletion mutant expressed in HBE cells assessed as change in short circuit current incubated for 18 to 24 hrs in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed