BDBM50596991 CHEMBL5194869

SMILES CC1(C)CCCC[C@@](O)(c2nnc(o2)-c2nc(OC1)c(cc2N)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=VGCFFRXWSDGNKE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50596991   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50596991(CHEMBL5194869)
Affinity DataEC50: <500nMAssay Description:Modulation of CFTR F508 deletion mutant expressed in HBE cells assessed as change in short circuit current incubated for 18 to 24 hrs in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed