BDBM50597019 CHEMBL5197040

SMILES Fc1ccc(C(NC(=O)[C@@H]2CNC(=O)C2)c2cnc(c(Cl)c2)C(F)(F)F)c(F)c1Cl

InChI Key InChIKey=XLYGMWFKGSHCJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50597019   

TargetSodium channel protein type 8 subunit alpha(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50597019(CHEMBL5197040)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human Nav1.8 channel stably expressed in HEK293 cells assessed as sodium current flow at holding potential of -90mV by whole-cell volta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed