BDBM50597117 CHEMBL5183596::US20230287003, Example 9a

SMILES C[C@H]1COCc2c(N1)c1cc(Nc3ccnc(Cl)c3C#N)ccc1n(C)c2=O

InChI Key InChIKey=URBCFCHCJQINQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597117   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50597117(CHEMBL5183596 | US20230287003, Example 9a)
Affinity DataIC50: 2.19E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained 1 nM Trx-6×His-BCL6 (in house-produced, human BCL6 BTB domain c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50597117(CHEMBL5183596 | US20230287003, Example 9a)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human N-terminal thioredoxin 6-His tagged BCL6 BTB domain (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed