BDBM50597174 CHEMBL5170423

SMILES Cc1[nH]nc(c1-c1ccc(-c2cccc(c2)S(N)(=O)=O)c(c1)C#N)-c1ccncc1

InChI Key InChIKey=VZXNVMSTYUKSGM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597174   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597174(CHEMBL5170423)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of full-length wild type LRRK2 (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADAPTA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597174(CHEMBL5170423)
Affinity DataEC50:  1.96E+4nMAssay Description:Inhibition of mouse full-length LRRK2 G2019S mutant transfected in HEK293 cells using LRRKtide as substrate in presence of ATP by incubated for 1 hr ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597174(CHEMBL5170423)
Affinity DataIC50:  323nMAssay Description:Inhibition of full-length LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed