BDBM50597244 CHEMBL5190385

SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(o2)-c2ccc(Cl)cc2)c(F)c1

InChI Key InChIKey=MPCOMZUFDSQYDC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597244   

TargetN-formyl peptide receptor 2(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50597244(CHEMBL5190385)
Affinity DataIC50: 28nMAssay Description:Agonist activity at human FPR2 in human HL-60 cells assessed as inhibition of chemotaxis by measuring reduction in cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetN-formyl peptide receptor 2(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50597244(CHEMBL5190385)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human FPR2 overexpressing CHO cells assessed as reduction in intracellular cAMP level incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetfMet-Leu-Phe receptor(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50597244(CHEMBL5190385)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human FPR1 overexpressing CHO cells assessed as reduction in intracellular cAMP level incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed