BDBM50597272 CHEMBL5209188

SMILES Fc1ccc2ccc(=O)n3CC(C[C@H]4OC[C@@H](CO4)NCc4cc5SCCOc5nn4)c1c23

InChI Key InChIKey=WGVXAOOUMDQJAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597272   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597272(CHEMBL5209188)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597272(CHEMBL5209188)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597272(CHEMBL5209188)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of hERG cardiac ion channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed