BDBM50597480 CHEMBL5207486

SMILES COc1cccc(c1)[C@@H](C)NC(=O)[C@H]1CC[C@H](CC1)c1ccncc1

InChI Key InChIKey=IQNOBOSIDWEVKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597480   

TargetRho-associated protein kinase 2(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597480(CHEMBL5207486)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetcGMP-dependent protein kinase 1(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597480(CHEMBL5207486)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human PKG expressed in baculovirus infected Sf9 insect cells using RSK as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed