BDBM50597523 CHEMBL1091913

SMILES N[C@@H](CCN(CC#C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O

InChI Key InChIKey=UUGVUWJWRVIDOL-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597523   

TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597523(CHEMBL1091913)
Affinity DataKd:  1.14E+4nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597523(CHEMBL1091913)
Affinity DataIC50: 7.71E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed