BDBM50597804 CHEMBL5201623

SMILES CC(C)n1cnc2c(nc(nc12)N1CCOCC1)-c1cccc(OCCCC(=O)NO)c1

InChI Key InChIKey=JSFJWFPAULATEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50597804   

TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50597804(CHEMBL5201623)
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50597804(CHEMBL5201623)
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC6 derived from human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50597804(CHEMBL5201623)
Affinity DataIC50: 35nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50597804(CHEMBL5201623)
Affinity DataIC50: 82nMAssay Description:Inhibition of HDAC1 derived from human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50597804(CHEMBL5201623)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-RHKK(Acetyl)-AMC peptide as fluorogenic substrate pre-incubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed