BDBM50597884 CHEMBL5185202

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCCCNCc2cccc(c2)-c2ccc(Cl)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=UDFJXRJYAZANFF-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50597884   

TargetProtein arginine N-methyltransferase 7(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PRMT7 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 140nMAssay Description:Inhibition of PRMT4 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 150nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PRMT1 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PRMT6 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of full length human recombinant PRMT7 extracted from Sf9 cells using biotinylated 3H-SAM as substrate incubated for 1 hr by TopCount scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to SARS-CoV-2 nsp14 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597884BDBM50597884(CHEMBL5185202)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of PRMT8 (unknown origin) incubated for 1 hr in presence of 3H-SAM by topcount plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed