BDBM50598483 CHEMBL5170759

SMILES CCOC(=O)c1nc(oc1C)-c1ccc(OC)cc1

InChI Key InChIKey=DAFRLXQGMZPMLA-UHFFFAOYSA-N

Data  2 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50598483   

TargetRISC-loading complex subunit TARBP2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598483BDBM50598483(CHEMBL5170759)
Affinity DataKd:  10nMAssay Description:Binding affinity to human recombinant TRBP by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRISC-loading complex subunit TARBP2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598483BDBM50598483(CHEMBL5170759)
Affinity DataKd:  15nMAssay Description:Binding affinity to 6His tagged recombinant TRBP (unknown origin) extracted from Escherichia coli BL21(DE3) assessed as dissociation constant by surf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProgrammed cell death protein 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598483BDBM50598483(CHEMBL5170759)
Affinity DataEC50:  2.25E+3nMAssay Description:Inhibition of PDCD4 in human HeLa cells tranfected with pCI-neo-luciferase-PDCD4 3'-UTR plasmid assessed as increase in luciferase activity by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRISC-loading complex subunit TARBP2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50598483BDBM50598483(CHEMBL5170759)
Affinity DataEC50:  3.01E+3nMAssay Description:Inhibition of TRBP in human HeLa cells transfected with pCIneo-luciferase microRNA-21 by measuring effective concentration in inhibition of microRNA-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed