BDBM50598492 CHEMBL5205694

SMILES C[C@H]1CC(=O)c2ccc(Nc3cc4c(cnc(OC5CC5)c4cn3)[C@](C)(N)C3CC3)cc2C11CC1

InChI Key InChIKey=GWYYJSPXAHPDSQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598492   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598492(CHEMBL5205694)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of HPK1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetInterleukin-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598492(CHEMBL5205694)
Affinity DataEC50:  9.40nMAssay Description:Inhibition of IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed