BDBM50598879 CHEMBL5188980

SMILES NCc1nccn1[C@H]1C[C@@H](N(C1)C(=O)c1cnc2[nH]ccc2c1)c1nc2ccccc2n1Cc1ccccc1

InChI Key InChIKey=KQGVGWAIXJGROB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598879   

TargetIndolethylamine N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50598879(CHEMBL5188980)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant INMT (1 to 263 residues) expressed in Escherichia coli BL21 (DE3) cells using S-(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50598879(CHEMBL5188980)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50598879(CHEMBL5188980)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NNMT in HEK293 cells measured after 20 to 24 hrs by RapidFire Mass SpectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed