BDBM50598891 CHEMBL5200510

SMILES Cc1ccc2n(Cc3ccc(Cl)cc3)c(nc2c1)[C@H]1C[C@@H](CN1C(=O)c1cnc2[nH]ccc2c1)n1ccnc1CN

InChI Key InChIKey=DAQWYPCUWSCNSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598891   

TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50598891(CHEMBL5200510)
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50598891(CHEMBL5200510)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of NNMT in HEK293 cells measured after 20 to 24 hrs by RapidFire Mass SpectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed