BDBM50598936 CHEMBL5180636

SMILES Clc1cccc(c1)-c1nccc2c3ccccc3[nH]c12

InChI Key InChIKey=JZPFJROBBBOMNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598936   

TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598936(CHEMBL5180636)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598936(CHEMBL5180636)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed