BDBM50598959 CHEMBL5184827

SMILES COCCCn1cc(CN(C2CC2)C(=O)[C@H]2CNCCO2)c2cccnc12

InChI Key InChIKey=AYCFHBROWDHEFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598959   

TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598959(CHEMBL5184827)
Affinity DataIC50: 159nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRenin(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598959(CHEMBL5184827)
Affinity DataIC50: 661nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed