BDBM50599375 CHEMBL5181874

SMILES O=C1C=CC2(OCC(Cc3cn(nn3)-c3cccc(Cc4ccccc4)c3)C(=O)N2c2ccccc2)C=C1

InChI Key InChIKey=OTEGXLWHPYDRNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599375   

TargetGlycogen synthase kinase-3 beta(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50599375(CHEMBL5181874)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50599375(CHEMBL5181874)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using 3H-SAM as substrate incubated for 1 hr by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed