BDBM50599470 CHEMBL5179796
SMILES Oc1ccc2nc(NC(=O)Nc3ccc(NC(=O)Cc4ccccc4)cc3)sc2c1
InChI Key InChIKey=HCNOPAFXBMHAAV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50599470
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK1A in human HeLa cells transiently expressing GFP-SF3B1 fusion protein assessed as reduction in SF3B1 phosphorylation incubated for...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair