BDBM50599876 CHEMBL5187721
SMILES Fc1cc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)ccc1Cl
InChI Key InChIKey=DGIHILWHEUNSHI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50599876
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Binding affinity to sigma 1 receptor in human Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.52E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair