BDBM50599876 CHEMBL5187721

SMILES Fc1cc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)ccc1Cl

InChI Key InChIKey=DGIHILWHEUNSHI-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50599876   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to sigma 1 receptor in human Jurkat cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor in HEK293 cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599876(CHEMBL5187721)
Affinity DataIC50:  1.51E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed