BDBM50599879 CHEMBL5181334

SMILES Cn1cnc2cc(CN3CCC(CC3)OCc3cccc(c3)C(F)(F)F)ccc12

InChI Key InChIKey=IJLHWQBSZFONAR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599879   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599879(CHEMBL5181334)
Affinity DataKi:  12nMAssay Description:Displacement of [3H] Pentazocine from sigma 1 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599879(CHEMBL5181334)
Affinity DataKi:  640nMAssay Description:Displacement of [3H]N-methylspiperone from D4 receptor in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599879(CHEMBL5181334)
Affinity DataKi:  640nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599879(CHEMBL5181334)
Affinity DataIC50: 646nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK293 cell membrane by competitive inhibition based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed