BDBM50599919 CHEMBL5174434

SMILES OC(=O)CC1CCC2(CC1)CCC(CC2)c1ccc(NC(=O)c2nnc(Nc3ccc(F)c(F)c3)o2)cc1

InChI Key InChIKey=OQWPAKFHAYCXAX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50599919   

TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 15nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599919(CHEMBL5174434)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed