BDBM50599920 CHEMBL5202474

SMILES OC(=O)CC1CCC2(CC1)CCC(CC2)c1ccc(NC(=O)c2nnc(Nc3ccc(F)c(F)c3)o2)cn1

InChI Key InChIKey=QKTPNXWLDUSRAW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599920   

TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599920(CHEMBL5202474)
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599920(CHEMBL5202474)
Affinity DataIC50: 17.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599920(CHEMBL5202474)
Affinity DataIC50: 18nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599920(CHEMBL5202474)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed