BDBM50599972 CHEMBL5205937

SMILES C[C@@H]1COc2cn3ncc4C(=O)NC(C)(C)COc5cc(F)ccc5CN1c2nc34

InChI Key InChIKey=HVIJVFYUUAELBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599972   

TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50599972(CHEMBL5205937)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50599972(CHEMBL5205937)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50599972(CHEMBL5205937)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed