BDBM50600004 CHEMBL5184104

SMILES [H][C@]12C[C@H](CC[C@]1([H])N(C(=O)O2)c1ccc2OCC(=O)Nc2n1)NCCn1c2cc(OC)cnc2ccc1=O

InChI Key InChIKey=QNIRZGVLRPNLDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600004   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 220nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed