BDBM50600044 CHEMBL5185866

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCCCCCCC(=O)NO

InChI Key InChIKey=NWHRMDIXMQBLHY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50600044   

TargetHistone deacetylase 6(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence based micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 46nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 85nMAssay Description:Inhibition of PD-1/PDL1 interaction (unknown origin) in by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 172nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys-(triflouroacetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50600044(CHEMBL5185866)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed