BDBM50600128 CHEMBL5209173::US20240336588, Compound 53

SMILES Oc1cc(cc(O)c1O)[C@@H]1Cc2ccccc2C[C@H]1OC(=O)c1cc(O)c(O)c(O)c1

InChI Key InChIKey=RCIOEYZEWSYXGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600128   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Avanti Biosciences

US Patent
LigandPNGBDBM50600128(CHEMBL5209173 | US20240336588, Compound 53)
Affinity DataIC50: 1.00E+3nMAssay Description:DYRK1A assay. Substrate, HT-PRD (Proline rich domain, residues 746-864 of dynamin 1a, prepared as N-terminal tagged 6×His fusion protein), was dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Avanti Biosciences

US Patent
LigandPNGBDBM50600128(CHEMBL5209173 | US20240336588, Compound 53)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed