BDBM50600258 CHEMBL5201543

SMILES CN1CCC(CC1)c1ccc(cc1)-c1ccc2CN(C(C(=O)Nc3nccs3)c3cc(F)ccc3O)C(=O)c2c1

InChI Key InChIKey=SYTVDTWRIZNVEW-UHFFFAOYSA-N

Data  1 IC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600258   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50600258(CHEMBL5201543)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of his-GST tagged human EGFR L858R/T790M double mutant expressed in insect cells incubated for 30 mins in presence of ATP by HTRF kinase a...More data for this Ligand-Target Pair