BDBM50600263 CHEMBL5202129

SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2C(=O)N(CCc2c1)C(C(=O)Nc1nccs1)c1cccc(F)c1

InChI Key InChIKey=WYQYLTBQKBAUCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600263   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50600263(CHEMBL5202129)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of his-GST tagged human EGFR L858R/T790M double mutant expressed in insect cells incubated for 30 mins in presence of ATP by HTRF kinase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed