BDBM50600266 CHEMBL5195912

SMILES CN1CCC(CC1)c1ccc(cc1)-c1ccc2CCN(C(C(=O)Nc3nccs3)c3cccc(F)c3)C(=O)c2c1

InChI Key InChIKey=XKSYIHZOSLKUBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50600266   

TargetEpidermal growth factor receptor(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50600266(CHEMBL5195912)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of his-GST tagged human EGFR L858R/T790M double mutant expressed in insect cells incubated for 30 mins in presence of ATP by HTRF kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed