BDBM50600273 CHEMBL5172573
SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2ncn(C(C(=O)Nc3nccs3)c3ccccc3)c(=O)c2c1
InChI Key InChIKey=RCQUCWWKJWPZAY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50600273
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of his-GST tagged human EGFR L858R/T790M double mutant expressed in insect cells incubated for 30 mins in presence of ATP by HTRF kinase a...More data for this Ligand-Target Pair