BDBM50600307 CHEMBL5185244

SMILES O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCC(CC2)n2cccn2)n1

InChI Key InChIKey=JFSZGTXFEWOOQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600307   

TargetTyrosine-protein kinase JAK2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50: 52nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50: 57nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50: 97nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed