BDBM50600308 CHEMBL5174885

SMILES Cc1nnc(s1)C1CCN(CC1)c1ccc(Nc2nccc(n2)-c2ccc(cc2)C(=O)NCC#N)cc1

InChI Key InChIKey=RJSRGYNITUBKSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600308   

TargetTyrosine-protein kinase JAK1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50: 18nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50: 22nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50: 102nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed