BDBM50600311 CHEMBL5171066

SMILES Cc1ccc(o1)C1CCN(CC1)c1ccc(Nc2nccc(n2)-c2ccc(cc2)C(=O)NCC#N)cc1

InChI Key InChIKey=RCIYSHDQTFGLIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600311   

TargetTyrosine-protein kinase JAK2(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600311(CHEMBL5171066)
Affinity DataIC50: 500nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600311(CHEMBL5171066)
Affinity DataIC50: 500nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600311(CHEMBL5171066)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed