BDBM50600520 CHEMBL5174426

SMILES NC(=O)c1cc2c(ccc(F)c2s1)-c1ccc(s1)C(=O)NCc1cccc(N)c1

InChI Key InChIKey=SHXMQMOAEGLRHE-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600520   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Ach£

Curated by ChEMBL

LigandBDBM50600520(CHEMBL5174426)Copy SMILESCopy InChI

Affinity DataKi:  491nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Ach£

Curated by ChEMBL

LigandBDBM50600520(CHEMBL5174426)Copy SMILESCopy InChI

Affinity DataKi:  2.31E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy BDB DOIPubMed
Copy reaction URL