BDBM50601242 CHEMBL5169601

SMILES Cn1cnc(Cc2cc(=O)n3nc(Nc4c5CCCc5cc5CCCc45)nc3[nH]2)c1

InChI Key InChIKey=GAULZBAEXQAKAP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50601242   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50601242(CHEMBL5169601)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-pretreated PBMC (unknown origin) assessed as reduction in IL-1beta release pretreated for 30 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/24/2023
Entry Details
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