BDBM50603042 CHEMBL5179131

SMILES N#Cc1ccc2C(CCOc2c1)Nc1ccc2[nH]nc(-c3ccncc3)c2c1

InChI Key InChIKey=VWXCQCAVLRAQIE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50603042   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603042(CHEMBL5179131)
Affinity DataIC50:  61nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603042(CHEMBL5179131)
Affinity DataEC50:  160nMAssay Description:Inhibition of pcDNA5FRT-TO-GFP fused - LRRK2 G2019S mutant (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603042(CHEMBL5179131)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of wild type pcDNA5FRT-TO-GFP fused - LRRK2 (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603042(CHEMBL5179131)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed