BDBM50604029 CHEMBL5176371::US20230312529, Compound 6a

SMILES Cc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1Nc1ccc2cn[nH]c2c1

InChI Key InChIKey=BROXUXZMHQXSGO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604029   

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604029(CHEMBL5176371 | US20230312529, Compound 6a)
Affinity DataIC50: 4.20nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandPNGBDBM50604029(CHEMBL5176371 | US20230312529, Compound 6a)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604029(CHEMBL5176371 | US20230312529, Compound 6a)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604029(CHEMBL5176371 | US20230312529, Compound 6a)
Affinity DataIC50: 17nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent