BDBM50604190 CHEMBL5178885

SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)CCCCNc2c3CCCCc3nc3cc(Cl)ccc23)cc1

InChI Key InChIKey=LCWAVZISUIFMQY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50604190   

TargetAcetylcholinesterase(Mouse)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604190(CHEMBL5178885)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant mouse AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604190(CHEMBL5178885)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604190(CHEMBL5178885)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604190(CHEMBL5178885)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant mouse sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604190(CHEMBL5178885)
Affinity DataIC50: 179nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed