BDBM50604191 CHEMBL5207628

SMILES [H][C@]12Cc3nc4cc(Cl)ccc4c(NCCCCC(=O)N4CCC(CC4)NC(=O)Nc4ccc(OC(F)(F)F)cc4)c3[C@]([H])(CC(C)=C1)C2

InChI Key InChIKey=VPHLBLQNXMWQOL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50604191   

TargetBifunctional epoxide hydrolase 2(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604191(CHEMBL5207628)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604191(CHEMBL5207628)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Mouse)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604191(CHEMBL5207628)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant mouse AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604191(CHEMBL5207628)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant mouse sEH using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured every 30 sec for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50604191(CHEMBL5207628)
Affinity DataIC50: 615nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed