BDBM50604324 CHEMBL5183361

SMILES Cc1ccc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)NC(C)(C)C)NC(=O)CCNC(=O)C(=C\c2ccco2)\C#N)cc1

InChI Key InChIKey=VTKSMYDOQHZUPK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50604324   

TargetProteasome subunit beta type-8(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of 20S proteasome subunit beta-5c (unknown origin) using Ac-WLA-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-10(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-2i (unknown origin) using Ac-KQL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-4(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-2c (unknown origin) using Ac-KQL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-1i (unknown origin) using Ac-PAL-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 20S proteasome subunit beta-1c (unknown origin) using Z-LLE-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed