BDBM50604446 CHEMBL5200675

SMILES CN1CCN(Cc2ccc(NC(=O)c3cccc(\C=C\c4cnc5ccccc5c4)c3)cc2C(F)(F)F)CC1

InChI Key InChIKey=KWJVOGHZNRHTLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604446   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604446(CHEMBL5200675)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed