BDBM50604669 CHEMBL5208485

SMILES FC(F)(F)c1ccc(cc1)-c1noc(CN2CCCC(CN3CCOCC3)C2)n1

InChI Key InChIKey=VFQGZIAZHIRPPQ-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604669   

TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.00800nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.100nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(7-36)NH2 induced cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.25nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataIC50: 6.30nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion at 0.1 nM i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed