BDBM50605040 CHEMBL5200705

SMILES FC1(F)CCN(CC1)c1nc2ccccc2c2n(Cc3cccc(Cl)c3)ccc12

InChI Key InChIKey=PKKVQHSSLZVNAS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50605040   

TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 17nMAssay Description:Reversible inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataKi:  3.83E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed