BDBM50605259 CHEMBL5176505

SMILES COc1ccccc1C1=NN(C(=O)C1)c1ccccn1

InChI Key InChIKey=FHBSBNDBGZHUGX-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605259   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605259BDBM50605259(CHEMBL5176505)
Affinity DataIC50: 7nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605259BDBM50605259(CHEMBL5176505)
Affinity DataKd:  23nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MicroScale Thermophoresis (MST) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605259BDBM50605259(CHEMBL5176505)
Affinity DataKd:  46nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MST dimerization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed