BDBM50605266 CHEMBL5171729

SMILES COc1ccc(cc1)C1=NN(C(=O)C1)c1ccccn1

InChI Key InChIKey=DXWBEIPEDHYRHM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605266   

TargetProgrammed cell death 1 ligand 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605266BDBM50605266(CHEMBL5171729)
Affinity DataKd:  2nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MST dimerization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605266BDBM50605266(CHEMBL5171729)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605266BDBM50605266(CHEMBL5171729)
Affinity DataKd:  83nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MicroScale Thermophoresis (MST) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed