BDBM50605456 CHEMBL5200166

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc(Sc3cnc(cn3)N3CCC4(CO[C@@H](C)[C@H]4N)CC3)c(Cl)c2)ncc1F

InChI Key InChIKey=GYFNRQGETQTKEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605456   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605456(CHEMBL5200166)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST/His6-fusion tagged human CDK4/Cyclin D3 expressed in Sf9 insect cells using 5-FAM-IPTSPITTTYFFFKKK as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605456(CHEMBL5200166)
Affinity DataIC50: 61nMAssay Description:Inhibition of SHP2 (unknown origin) using DiFMUP as substrate incubated for 60 mins followed by substrate addition for 30 mins by microplate reader m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed