BDBM50605466 CHEMBL5194011

SMILES CCCSc1ncc2cc3cnccc3c(N)c2n1

InChI Key InChIKey=QKXNCBKBLXLGSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605466   

TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 148nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed